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. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jul 6;(7):CD001800. doi: 10.1002/14651858.CD001800.pub2
Methods Single-center, unblinded, single-centre RCT in China; f/u 2 y
Participants 269 patients (76% men; mean age 64 y) with recent AMI (n=193) or after elective percutaneous coronary intervention (n=76)
EX: n=181 (mean age, 64 SD 11 y; 138 males, 43 females)
UC: n=88 (mean age, 64 SD 11 y; 66 males, 22 females)
Interventions EX : Phase 1 was impatient ambulatory program that lasted 7-14 d; phase 2 was 16-session, twice weekly, outpatient exercise and education program lasting for 8 weeks, each session included 1 hr of education class followed by 2 hrs of exercise training, 1st hour oftraining was conducted by physiotherapist; phase 3 was community-based home exercise program for another 6 mos; phase 4 was long-term follow-up program until end of 2 years which stressed importance of regular exercise and risk factor modification
UC: attended 2-hr talk that explained CHD, importance of risk factor modification, and potential benefits of physical activity, but without undergoing outpatient exercise training program
Outcomes Total mortality
Notes
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Unclear risk “randomized”
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding (performance bias and detection bias)
All outcomes
Unclear risk “The QOL assessments were performed on all patients in all 4 phases by a trained social worker who was unaware of the randomization”
Unclear in terms ofassessment ofother outcomes.
Incomplete outcome data (attrition bias)
All outcomes
High risk 24 % lost to follow up, no description of withdrawals or dropouts
Selective reporting (reporting bias) Unclear risk No information reported.