Methods | Randomised 6 weeks post admission | |
Participants | N: 303 (EX n=151; CON n=152) 100% men Mean age: EX = 50.3 (SE 0.65) years CON =52.8 (SE 0.67) years Diagnosis: MI Ethnicity: NR Inclusion: MI patients admitted to the coronary care unit; diagnosis based on ECG changes and /or elevation of serum glutamic oxaloacetic transaminase or lactic dehydro-genase taken on three consecutive days ExclusIon: >70 years; heart failure at follow-up clinic; cardio-thoracic ratio exceeding 59%; severe chronic obstructive lung disease; hypertension requiring treatment; diabetes requiring insulin; disabling angina during convalescence; orthopaedic or medical disorders likely to impede progress in the gym, personality disorders likely to render patient unsuitable for the course |
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Interventions | Exercise group: Duration: 12 weeks; Frequency: attended gym 2 × weekly : Mode: Exercises arranged on a circuit basis and pure isometric exercise was avoided. Control group: Did not attend gym |
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Outcomes | Total mortality, non fatal MI at 5 months, 1 year, 2 year and 3 year after MI (mean F/U 2.1 years) | |
Notes | There appears to be a reduction in mortality in exercise participants with inferior MI | |
Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | “randomly allocated” |
Allocation concealment (selection bias) | Unclear risk | Not reported. |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk | Unclear in terms of assessment of outcomes. |
Incomplete outcome data (attrition bias) All outcomes |
High risk | 21% lost to follow up, no description of withdrawals or dropouts |
Selective reporting (reporting bias) | Unclear risk | No information reported. |