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. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jul 6;(7):CD001800. doi: 10.1002/14651858.CD001800.pub2
Methods Randomised 6 weeks post admission
Participants N: 303 (EX n=151; CON n=152)
100% men
Mean age: EX = 50.3 (SE 0.65) years CON =52.8 (SE 0.67) years
Diagnosis: MI
Ethnicity: NR
Inclusion: MI patients admitted to the coronary care unit; diagnosis based on ECG changes and /or elevation of serum glutamic oxaloacetic transaminase or lactic dehydro-genase taken on three consecutive days
ExclusIon: >70 years; heart failure at follow-up clinic; cardio-thoracic ratio exceeding 59%; severe chronic obstructive lung disease; hypertension requiring treatment; diabetes requiring insulin; disabling angina during convalescence; orthopaedic or medical disorders likely to impede progress in the gym, personality disorders likely to render patient unsuitable for the course
Interventions Exercise group: Duration: 12 weeks; Frequency: attended gym 2 × weekly : Mode: Exercises arranged on a circuit basis and pure isometric exercise was avoided.
Control group: Did not attend gym
Outcomes Total mortality, non fatal MI at 5 months, 1 year, 2 year and 3 year after MI (mean F/U 2.1 years)
Notes There appears to be a reduction in mortality in exercise participants with inferior MI
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Unclear risk “randomly allocated”
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding (performance bias and detection bias)
All outcomes
Unclear risk Unclear in terms of assessment of outcomes.
Incomplete outcome data (attrition bias)
All outcomes
High risk 21% lost to follow up, no description of withdrawals or dropouts
Selective reporting (reporting bias) Unclear risk No information reported.