Table 2.
Demographics of participants according to APOE E4 status.
| E4 noncarrier | E4 carrier | P | |
|---|---|---|---|
| Number (%) | 8492 (83.3%) | 1698 (16.7%) | |
| Age, y | 61.6 ± 7.8 | 61.5 ± 7.7 | 0.494 |
| Women, % | 60.4 | 62.0 | 0.220 |
| Formal education, (%) | |||
| None | 34.8 | 34.5 | 0.839 |
| 1~6 years | 40.3 | 40.4 | |
| More than 9 years | 24.9 | 25.1 | |
| CES-DK | 52.1 ± 8.6 | 52.5 ± 8.4 | 0.139 |
| Current smoker, % | 15.4 | 14.7 | 0.432 |
| Current drinker, % | 47.6 | 46.4 | 0.369 |
| Hypertension, % | 40.0 | 39.3 | 0.574 |
| Type 2 diabetes, % | 13.5 | 13.1 | 0.656 |
| Hyperlipidemia, % | 10.2 | 13.0 | 0.001 |
| Body mass index, kg/m2 | 24.4 ± 3.1 | 24.4 ± 3.1 | 0.756 |
| Systolic blood pressure, mmHg | 126.1 ± 18.3 | 125.7 ± 18.4 | 0.415 |
| Diastolic blood pressure, mmHg | 80.5 ± 10.2 | 80.3 ± 10.1 | 0.543 |
| Fasting blood glucose, mg/dL | 104.9 ± 24.0 | 104.0 ± 23.4 | 0.148 |
| UACR, mg/g | 44.7 ± 146.7 | 43.0 ± 161.6 | 0.654 |
| eGFR*, µmol/L | 77.7 ± 14.6 | 78.4 ± 14.5 | 0.049 |
Data are expressed as mean ± SD or percentages. CES-D-K: the Center for Epidemiological Study-Depression Scale Korean version, UACR: urinary albumin-to-creatinine ratio, and eGFR: estimated glomerular filtration rate.
*eGFR was calculated with the 4-variable modification of diet in renal disease (MDRD) formula.
P values are shown for chi-square tests and t-tests, as appropriate.