Table 2.
Multivariable models of the association of adiposity measures with AKI, primary analysis (n=327).
| 2a. VAT area (C-statistic 0.730, 95% CI 0.661,0.799) |
| Characteristic | Odds ratio (95% CI) | p |
|---|---|---|
|
| ||
| VAT area, per SD | 1.60 (1.20,2.14) | 0.001 |
| African American race | 1.68 (0.84,3.36) | 0.142 |
| Diabetes | 3.39 (1.23,9.31) | 0.018 |
| Blunt trauma mechanism | 0.62 (0.26,1.48) | 0.283 |
| ISS, per SD | 1.44 (1.07,1.93) | 0.016 |
| PRBC, per unitb | 1.11 (1.04,1.19) | 0.002 |
| Crystalloid, per literb | 1.03 (0.92,1.15) | 0.619 |
| 2b. SAT area (C-statistic 0.730, 95% CI 0.663,0.797) |
| Characteristic | Odds ratio (95% CI) | p |
|---|---|---|
|
| ||
| SAT area, per SD | 1.45 (1.08,1.93) | 0.012 |
| Age, per 10 years | 1.12 (0.94,1.34) | 0.207 |
| Diabetes | 2.95 (1.07,8.11) | 0.038 |
| Blunt trauma mechanism | 0.43 (0.19,0.99) | 0.046 |
| ISS, per SD | 1.43 (1.07,1.92) | 0.016 |
| PRBC, per unitb | 1.11 (1.04,1.19) | 0.003 |
| Crystalloid, per literb | 1.02 (0.92,1.15) | 0.673 |
| 2c. BMIa (C-statistic 0.738, 95% CI 0.672,0.804) |
| Characteristic | Odds ratio (95% CI) | p |
|---|---|---|
|
| ||
| BMI, per SD | 1.55 (1.17,2.07) | 0.003 |
| Age, per 10 years | 1.11 (0.92,1.33) | 0.266 |
| Diabetes | 3.24 (1.17,8.99) | 0.024 |
| Blunt trauma mechanism | 0.52 (0.23,1.18) | 0.119 |
| ISS, per SD | 1.40 (1.04,1.88) | 0.025 |
| PRBC, per unitb | 1.10 (1.03,1.18) | 0.004 |
| Crystalloid, per literb | 1.02 (0.91,1.14) | 0.751 |
a
BMI model n=326 due to unavailable height and weight for one subject.
b
Administered during resuscitation prior to ICU admission.
Definition of abbreviations: AKI=acute kidney injury; CI= confidence interval; VAT=visceral adipose tissue; SD=standard deviation ; ISS= Injury Severity Score; PRBC= packed red blood cells; SAT=subcutaneous adipose tissue; BMI= body-mass index.