Figure 4.

PSMD9 expression is functionally associated with RT response in breast cancer cells. Breast cancer cell lines were transiently transfected with siRNAs targeting PSMD9 or with non-targeting control. A PSMD9 was effectively silenced using siRNA, as demonstrated using Western blotting of MCF7 transfected lysates. B MCF7 cell growth after 48 h was unaffected by PSMD9 knock-down, as demonstrated using MTT survival/proliferation assays. C PSMD9 knock-down enhanced the efficacy of RT in breast cancer cell lines, as demonstrated using colony forming assays. Data points represent means of triplicates (+/- standard deviations).