Figure 3.

Upregulation of CXCL12 inhibits the growth of breast cancer cells in vivo and in vitro. A: Colony formation assay. B: MTT proliferation assay. MDA-MB-231 and Ad-CXCL12 cell lines were injected into right scapular region of nude mice (each group = 7). 3 weeks later, the mice were sacrificed, photographed, dissected and the weight of tumor were counted. C: The photograph of excised tumors from each group terminated in 3 weeks. D: The mean weight of each group. All results were reproducible in three independent experiments.