Table 1.
Correlation between the expression of KLF4 protein and patients’ clinical characteristics
| Pathological factors | Case (N) | expression of KLF4 protein | x 2 value | P value | |
|---|---|---|---|---|---|
|
| |||||
| Negative (55) | Positive (43) | ||||
| Gender | |||||
| Male | 64 | 37 (57.8%) | 27 (42.2%) | 0.214 | 0.644 |
| Female | 34 | 18 (52.9%) | 16 (47.1%) | ||
| Age (yr) | |||||
| ≤60 | 50 | 32 (64.0%) | 18 (36.0%) | 3.442 | 0.064 |
| >60 | 48 | 23 (47.9%) | 25 (52.1%) | ||
| The location of the tumor | |||||
| The upper esophagus | 7 | 5 (71.4%) | 2 (28.6%) | 5.748 | 0.056 |
| Esophageal | 65 | 31 (47.7%) | 34 (52.3%) | ||
| The lower esophagus | 26 | 19 (73.1%) | 7 (26.9%) | ||
| Tumor diameter (cm) | |||||
| <5 | 54 | 28 (51.9%) | 26 (48.1%) | 0.891 | 0.345 |
| ≥5 | 44 | 27 (61.4%) | 17 (38.6%) | ||
| Differentiation degree | |||||
| I, I-II, II | 87 | 49 (56.3%) | 38 (43.7%) | 0.013 | 0.911 |
| II-III, III | 11 | 6 (54.5%) | 5 (45.5%) | ||
| T Staging | |||||
| T1 | 8 | 3 (37.5%) | 5 (62.5%) | 1.479 | 0.477 |
| T2 | 19 | 10 (52.6%) | 9 (47.4%) | ||
| T3 | 71 | 42 (59.2%) | 29 (40.8%) | ||
| Lymph node metastsis | |||||
| No | 57 | 24 (42.1%) | 33 (57.9%) | 10.871 | 0.001 |
| Yes | 41 | 31 (75.6%) | 10 (24.4%) | ||
| TNM Staging | |||||
| Stage I | 8 | 3 (37.5%) | 5 (62.5%) | 6.482 | 0.039 |
| Stage IIA-IIB | 49 | 23 (46.9%) | 26 (53.1%) | ||
| Stage III | 41 | 29 (70.7%) | 12 (29.3%) | ||