Figure 2.
Survival curves for 98 esophageal squamous cell carcinoma (ESCC) patients according to expression patterns of miR-195 and Cdc42 mRNA in tumor tissues. Kaplan-Meier analysis showed that the OS of ESCC patients with low miR-195 expression or high Cdc42 mRNA expression were markedly shorter than that with high miR-195 expression or low Cdc42 mRNA expression (both P < 0.001; A and C). Similar results were also observed in the DPFS analysis (both P < 0.001; B and D). In addition, the OS and DPFS of patients with combined low-miR-195 and high-Cdc42 mRNA expression (miR-195-low/Cdc42-high) were the shortest (both P < 0.001, E and F) when compared with patients in other three groups (miR-195-low/Cdc42-low, miR-195-high/Cdc42-high, miR-195-high/Cdc42-low).