Table 1.
Associations of microRNA (miR)-195 or Cdc42 mRNA expression with clinicopathological characteristics of 98 esophageal squamous cell carcinoma (ESCC) patients
| Clinical variables | No. of patients (n, %) | MiR-195-low (n, %) | P | Cdc42-high (n, %) | P |
|---|---|---|---|---|---|
| Gender | |||||
| Male | 68 (69.39) | 36 (52.94) | NS | 36 (52.94) | NS |
| Female | 30 (30.61) | 16 (53.33) | 14 (46.67) | ||
| Age (year) | |||||
| > 60 | 56 (57.14) | 30 (53.57) | NS | 30 (53.57) | NS |
| ≤ 60 | 42 (42.86) | 22 (52.38) | 20 (47.62) | ||
| Tumor size (cm) | |||||
| > 5 | 58 (59.18) | 30 (51.72) | NS | 30 (51.72) | NS |
| ≤ 5 | 40 (40.82) | 22 (48.28) | 20 (50.00) | ||
| Tumor location | |||||
| Upper | 52 (46.67) | 32 (61.54) | NS | 30 (57.69) | NS |
| Middle/Lower | 46 (33.33) | 20 (43.48) | 20 (43.48) | ||
| TNM stage | |||||
| I | 15 (15.31) | 0 (0) | 0.008 | 2 (13.33) | 0.011 |
| II | 43 (43.88) | 17 (39.53) | 15 (34.88) | ||
| III | 25 (25.51) | 20 (80.00) | 18 (72.00) | ||
| IV | 15 (15.31) | 15 (100.0) | 15 (100.0) | ||
| Tumor differentiation | |||||
| Well~Moderately | 52 (53.06) | 26 (50.00) | NS | 22 (42.31) | 0.024 |
| Poorly | 46 (46.94) | 26 (56.52) | 28 (60.87) | ||
| Lymphatic metastasis | |||||
| Yes | 40 (16.67) | 30 (75.00) | 0.022 | 24 (60.00) | NS |
| No | 58 (37.50) | 22 (37.93) | 26 (44.83) | ||
| Venous invasion | |||||
| Yes | 42 (42.86) | 21 (50.00) | NS | 21 (50.00) | NS |
| No | 56 (57.14) | 31 (55.36) | 29 (51.79) |