Table 2.
Association of TP53 expression with patient 24 months mortality
| Studies | Cases/total cases | I2 (%) | Risk ratio (95% CI) |
|---|---|---|---|
| All | 13/428) | 13.26 | 1.94 [1.43, 2.64] |
| IHC only | 8/288 | 7 | 2.05 [1.33, 3.15] |
| Studies on expression | 9/320 | 14 | 1.81 [1.24, 2.66] |
| Studies on mutation | 4/108 | 0 | 2.28 [1.38, 3.77] |
| Treatment: NC + surgery | 10/339 | 0 | 2.06 [1.41, 3.02] |
| Treatment: surgery only | 3/89 | 72 | 1.84 [0.75, 4.52] |
| Sensitivity analyses | |||
| Specific 10% cutoff | 7/256 | 12 | 2.22 [1.46, 3.40] |
Note: If the I2 value was less than 50%, a fixed-effects meta-analysis was applied. If the I2 value was 50% or more, the random-effects meta-analysis was used. Abbreviations: CI, confidence interval; NC, neoadjuvant chemotherapy.