Table 1.

Effect of chemotherapeutic agents on the growth of NSCLC cells transfected with Axl siRNA

Compounds	IC50 ± SDs μM (fold-reverse)
	A549	A549/siAxl
Doxorubicin	1.1004 ± 0.1022	0.7004 ± 0.0902 (1.57)*
Vincristine	0.0066 ± 0.0053	0.0018 ± 0.0012 (3.67)**
Paclitaxel	0.0017 ± 0.0134	0.0007 ± 0.0821 (2.43)**
	H460	H460/siAxl
Doxorubicin	12.0003 ± 1.0243	4.0124 ± 0.3002 (2.99)**
Vincristine	0.0014 ± 0.0091	0.0006 ± 0.0034 (2.33)**
Paclitaxel	0.0030 ± 0.0230	0.0011 ± 0.0149 (2.73)**

Cell survival was determined by MTT assays as described in “Materials and Methods”. Data are the means ± SDs of at least three independent experiments.

^* P < 0.05, for values versus that obtained in the parent cells;

^** P < 0.01, for values versus that obtained in the parent cells.