Table 3.
Expression of immunohischemical markers in 34 CNS GCTs
| Histology | PLAP | C-kit | OCT3/4 | HCG | AFP | CD30 | CK AE1/3 |
|---|---|---|---|---|---|---|---|
| G | + | + | + | - | - | - | - |
| STGC | - | - | - | + | - | + | + |
| G+EC | + | + | + | - | - | + | + |
| G+YST+EC | + | + | + | - | + | + | + |
| T(MT+IT) | - | - | - | - | - | - | + |
| EC | - | - | + | - | - | + | + |
| CC | + | - | - | + | - | - | + |
G: germinoma; MT: mature teratoma; IT: immature teratoma; MGCTs: mixed germ cell tumors; EC: embryonal carcinoma; YST: yolk sac tumor; CC: choriocarcinoma; STGCs: syncytiotrophoblastic giant cells.