Table 4.
Cox regression model analysis of disease-free survival (DFS) in 173 colon cancer patients
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
|
|
|
|||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | ||||
| < 65 y | 1 | |||
| ≥ 65 y | 1.133 (0.695, 1.848) | 0.616 | ||
| Gender | ||||
| Male | 1 | |||
| Female | 1.198 (0.737, 1.948) | 0.466 | ||
| Location | ||||
| Right | 1 | |||
| Transverse | 1.082 (0.417, 2.810) | 0.872 | ||
| Left | 1.055 (0.640, 1.738) | 0.834 | ||
| T stage | ||||
| T1 | 1 | |||
| T2 | 0.463 (0.077, 2.772) | 0.399 | ||
| T3 | 1.066 (0.248, 4.576) | 0.932 | ||
| T4 | 2.784 (0.674, 11.490) | 0.157 | ||
| N stage | ||||
| N0 | 1 | NR | ||
| N1 | 2.911 (1.622, 5.223) | < 0.001 | ||
| N2 | 10.685 (5.699, 20.034) | < 0.001 | ||
| M stage | ||||
| M0 | 1 | NR | ||
| M1 | 9.400 (4.489, 19.683) | < 0.001 | ||
| AJCC stage | ||||
| I | 1 | 1 | ||
| II | 1.726 (0.503, 5.924) | 0.386 | 1.435 (0.416, 4.944) | 0.567 |
| III | 6.017 (1.857, 19.495) | 0.003 | 4.092 (1.250, 13.395) | 0.020 |
| IV | 31.329 (8.245, 119.048) | < 0.001 | 11.759 (2.535, 54.556) | 0.002 |
| Differentiation | ||||
| Well | 1 | 1 | ||
| Moderate | 2.133 (1.221, 3.728) | 0.008 | 1.347 (0.749, 2.423) | 0.320 |
| Poorly | 4.967 (2.604, 9.477) | < 0.001 | 2.259 (1.021, 4.999) | 0.044 |
| Vessel invasion | ||||
| No | 1 | 1 | ||
| Yes | 3.173 (1.508, 6.673) | 0.002 | 0.851 (0.343, 2.108) | 0.727 |
| eIF3e | ||||
| Negative | 1 | 1 | ||
| Weak | 4.817 (1.484, 15.631) | 0.009 | 3.581 (1.079, 11.884) | 0.037 |
| Strong | 19.343 (5.842, 64.047) | < 0.001 | 10.281 (2.959, 35.728) | < 0.001 |
HR, Hazard ratio; CI, confidence interval; NR, variable was not include in the resultant model; P < 0.05 indicated that the 95% CI of HR was not including 1.