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. 2014 Oct 29;2014:158980. doi: 10.1155/2014/158980

Figure 5.

Figure 5

Cytokine profile. Percentage of total CD8 T cells and IFNγ or IL-10 producing CD8 cells, in peritumoral lymph nodes of mice with melanoma inoculated with BMDCs matured with TNFα and treated with MAGE-AX, GK-1, or MAGE-AX/GK-1. Mice treated with BMDCs MAGE/GK-1 showed increased levels of IFNγ in CD8+ lymphocytes. (a) Percentage of total CD8 T cells and IFNγ and IL-10 producers. * P < 0.05 GK-1 versus all groups. (b) MFI of IFNγ and IL-10 in CD8 T lymphocytes. * P < 0.05, c P < 0.05 GK-1 versus MAGE, + P < 0.05 MAGE/GK-1 versus MAGE. Without treatment (WT). Mean ± SEM n ≥ 3.