Table 2. Patients with and without tumor deposits following neoadjuvant chemoradiation.
Neoadjuvant chemoradiation +/tumor deposit + patients (n = 23) | Neoadjuvant chemoradiation + /tumor deposit − Patients (n = 87) | P-value | |
---|---|---|---|
Lymph node Involvement | 13/23 (57%) | 28/86 (33%) | 0.035 |
Perineural invasion | 6/23 (26%) | 4/85 (4%) | 0.002 |
Lymphovascular invasion | 6/22 (27%) | 10/85 (12%) | 0.069 |
Pretreatment stage T3/T4a | 12/12 (100%) | 37/43 (86%) | 0.170 |
Treatment response grade 0–1 | 5/23 (22%) | 29/87 (33%) | 0.285 |
5-Year local recurrence rate | 19% | 10% | 0.092 |
5-Year distant metastases rate | 51% | 30% | 0.006 |
Overall survival (years) | |||
Median survival | 3.1 | 11.2 | 0.027 |
1-Year survival | 86% | 92% |
Determined by endoscopic ultrasound.