Table 3.
The APOE allele frequencies in the African populations
| n | ε2 | ε3 | ε4 | p | |
|---|---|---|---|---|---|
|
North Africa |
|
|
|
|
|
| Mauritanians [35] |
20 |
0.08 |
0.83 |
0.1 |
0 |
| Moroccans [36] |
100 |
0.07 |
0.85 |
0.09 |
0 |
| Tunisians [37] |
180 |
0.04 |
0.87 |
0.09 |
0 |
|
West Africa |
|
|
|
|
|
| Ghanaians [32] |
110 |
0.15 |
0.61 |
0.24 |
0.89 |
| Gabonese [35] |
25 |
0.12 |
0.68 |
0.2 |
0.48 |
| Nigerians [38] |
365 |
0.03 |
0.68 |
0.3 |
0.03 |
| Bombareans (Mali) [35] |
16 |
0.06 |
0.72 |
0.22 |
0.12 |
| Guineans [35] |
30 |
0.23 |
0.6 |
0.17 |
0.1 |
| Beninese [19] |
97 |
0.1 |
0.74 |
0.16 |
0.11 |
| Togolese [35] |
19 |
0.32 |
0.47 |
0.21 |
0.01 |
| Djernas (Niger) [35] |
16 |
0.06 |
0.81 |
0.13 |
0.01 |
| Haoussas (Niger) [35] |
37 |
0.03 |
0.78 |
0.19 |
0.01 |
| Burkinabese [35] |
20 |
0.38 |
0.5 |
0.13 |
0 |
| Songhais (Mali) [35] |
17 |
0.21 |
0.74 |
0.06 |
0 |
| Senegalese [35] |
33 |
0.03 |
0.94 |
0.03 |
<0.0001 |
|
East Africa |
|
|
|
|
|
| Ethiopians [19] |
164 |
0.03 |
0.81 |
0.14 |
0 |
| Ugandans [33] |
140 |
0.16 |
0.59 |
0.25 |
0.85 |
| Tanzanians [34] |
143 |
0.14 |
0.65 |
0.21 |
0.66 |
| Rwandese [35] |
21 |
0.1 |
0.67 |
0.24 |
0.62 |
| Kenyans [34] |
61 |
0.09 |
0.59 |
0.32 |
0.5 |
|
Southern Africa |
|
|
|
|
|
| Zambians (current study) |
116 |
0.14 |
0.6 |
0.27 |
current study |
| Tswanas [32] |
100 |
0.15 |
0.57 |
0.29 |
0.86 |
| South Africans [2] |
505 |
0.190 |
0.52 |
0.29 |
0.43 |
| Sudanese [35] |
103 |
0.08 |
0.62 |
0.29 |
0.49 |
| Khoisans [39] |
247 |
0.08 |
0.55 |
0.37 |
0.2 |
| Malagasy [35] |
22 |
0.23 |
0.59 |
0.18 |
0.12 |
|
Central Africa |
|
|
|
|
|
| Central Africa Republicans (Pygmies) [35] |
70 |
0.06 |
0.54 |
0.41 |
0.05 |
| Congolese (Congo DR) [35] |
24 |
0.04 |
0.63 |
0.33 |
0.06 |
|
Other |
|
|
|
|
|
| Sub-Saharans(SSA) [35] | 470 | 0.12 | 0.71 | 0.18 | 0.27 |