Table 4.
The MTHFR C677T polymorphism allele frequencies in the African populations
| n | C | T | p | |
|---|---|---|---|---|
|
North Africa |
|
|
|
|
| Moroccans [36] |
182 |
0.73 |
0.27 |
<0.0001 |
|
West Africa |
|
|
|
|
| Gambians [40] |
24 |
0.94 |
0.06 |
0.69 |
| Nigerians [41] |
25 |
0.94 |
0.06 |
1 |
| Burkinabes [42] |
382 |
0.95 |
0.06 |
0.18 |
| Coastal Togolese [43] |
127 |
0.92 |
0.08 |
1 |
| Inland Togolese [43] |
68 |
0.94 |
0.06 |
0.58 |
| Coastal Beninese [43] |
270 |
0.9 |
0.1 |
0.85 |
| Ghanaians [44] |
174 |
0.92 |
0.08 |
1 |
|
East Africa |
|
|
|
|
| Kenyans [40] |
61 |
0.95 |
0.05 |
0.55 |
|
South Africa |
|
|
|
|
| Zambians |
116 |
0.91 |
0.09 |
Current study |
| Malagasy [40] |
97 |
0.93 |
0.07 |
0.61 |
|
Central Africa |
|
|
|
|
| Pygmies [40] |
8 |
0.94 |
0.06 |
1 |
|
Other |
|
|
|
|
| Bantu [40] |
44 |
0.91 |
0.09 |
1 |
| SSA [40] | 234 | 0.93 | 0.07 | 0.51 |