Fig 4.
Increase in T cell function is not due to changes in Treg numbers or altered CD39 expression. (A) Tregs were identified as CD25+ and FOXP3+ in the PBMCs of normal (black circle) and MuSK patients (square). The three unshaded squares represent patients who have received rituximab treatment. Frequency of Tregs were derived from total CD4 T cells. (B) CD39 expression in normal and MuSK patients was similar. The frequencies of CD39 were derived from CD25+FOXP3+ Tregs. Results are shown from ten normal individuals and eleven MuSK patients.