Table 5.

Most frequent stable combinations by specific drug ( N = 353)

Combinations by drug	Number of patients
Monotherapy
Lithium	21
Lamotrigine	20
Valproate	17
Bupropion	4
Quetiapine	4
Oxcarbazepine	3
Citalopram	2
Clonazepam	2
Paroxetine	2
Olanzapine	2
Two drugs
Lithium + lamotrigine	8
Lamotrigine + quetiapine	5
Lamotrigine + venlafaxine	5
Valproate + bupropion	4
Lamotrigine + clonazepam	4
Lithium + quetiapine	4
Valproate + lamotrigine	3
Lamotrigine + bupropion	3
Lamotrigine + citalopram	3
Lamotrigine + risperidone	3
Oxcarbazepine + fluoxetine	3
Oxcarbazepine + quetiapine	3
Bupropion + escitalopram	2
Carbamazepine + citalopram	2
Carbamazepine + lamotrigine	2
Valproate + quetiapine	2
Valproate + sertraline	2
Lamotrigine + fluvoxamine	2
Lamotrigine + escitalopram	2
Lamotrigine + fluoxetine	2
Lithium + venlafaxine	2
Lithium + olanzapine	2
Fluoxetine + olanzapine	2
Oxcarbazepine + bupropion	2
Venlafaxine + aripiprazole	2
Three drugs
Lamotrigine + clonazepam + quetiapine	2
Lamotrigine + venlafaxine + clonazepam	2
Lithium + carbamazepine + olanzapine	2
Lithium + lamotrigine + clonazepam	2
Lithium + lamotrigine + quetiapine	2
Lithium + lamotrigine + olanzapine	2
Four or more drugs
Lithium + lamotrigine + clonazepam + quetiapine	2
Lamotrigine + bupropion + paroxetine + quetiapine + aripiprazole	2

Only combinations taken by more than one patient included. Data from 167 (47%) of 353 patients and 43 (19%) of 231 unique combinations by drug.