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. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Circulation. 2009 Sep 15;120(11 0):S31–S36. doi: 10.1161/CIRCULATIONAHA.108.843979

Figure 3.

Figure 3

A. Myocardial infarct size (% of RA) measured 24 h post-MI in the various groups. Note that infarct size was significantly reduced with tadalafil, which was blocked by KT and PAG. B. The area-at-risk, expressed as percent of the left ventricle, was similar in all groups. C. Myocardial infarct size measured 24 h post-MI in C57BL wild-type mice, mice treated with DMSO or tadalafil, and in CSE-knockout mice. Note that genetic deletion of CSE abrogated the infarct-sparing effect of tadalafil. D. The area-at-risk was similar in C57BL wild-type mice, mice treated with DMSO or tadalafil, and in CSE-knockout mice.