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. 2014 Sep 26;3:11. doi: 10.1186/2045-9769-3-11

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© Yan et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Enhanced influenza A viral resistance in cultured fibroblasts isolated from transgenic pigs. (A) Ear fibroblasts isolated from Mx1 transgenic pigs and age-matched controls were infected with influenza A virus PR8 or NIBRG-14. After 24 hours, cells were fixed and stained for NP expression (red: NP, blue: nuclei; 4 × magnification). (B) Quantification of NP-positive cells. Values represent the mean ± s.d., n = 3. *P < 0.01 compared with the non-transgenic group.