TABLE 2.

Treatment delivery

	ARM A No. of patients	%	ARM B No. of patients	%	P
Induction chemotherapy
3 cycles	28	53.8	24	44.4	0.33
2 cycles	23	44.2	27	50.0	0.55
1 cycle	1	1.9	3	5.6	0.33
Concomitant chemotherapy
2 cycles	15	28.8	19	35.2	0.48
1 cycle	26	50	24	44.4	0.57
Incomplete 1 cycle	10	19.1	9	16.7	0.92
No chemotherapy	1	1.9	2	3.7	0.39
Radical radiotherapy
Started radical RT	50	100	53	98.1	0.54
Surgical treatment after induction chemotherapy	0	0	1 (pulmectomy)	1.9	0.32
RT doses >60 Gy	44	84.6	47	87.0	0.72
RT doses >56 Gy	48	92.4	53	98.1	0.16
PARAMETERS OF RADIOTHERAPY	ARM A		ARM B
GTV (cm3)
Median	123		124		0.98
Range	12–381		11–658
PTV (cm3)
Median	619		626		0.99
Range	133–1282		210–1428
V5 (%)
Median	64		61		0.52
Range	21–88		27–86
V20 (%)
Median	33		33		0.46
Range	12–56		20–52
V20 > 40%
No. of patients	12	24	6	12	0.12
MLD (Gy)
Median	20		19		0.34
Range	6–30		12–27
V50oes (%)
Median	47		42		0.06
Range	15–82		2–68
MoesD (Gy)
Median	35		32		0.17
Range	7–52		11–44

GTV = gross tumor volume; MoesD = mean esophagus dose in Gy; MLD = mean lung dose in Gy; No. = number; PTV = panning target volume; RT = radiotherapy; V5 = volume of lung receiving at least 5 Gy; V20 = volume of lung receiving at least 20 Gy; V50oes = volume of esophagus receiving at least 50 Gy