TABLE 3.
Toxicity of induction chemotherapy
| ARM A (n = 52) | ARM B (n = 54) | P* | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|||||||||
| Grade 1, 2 | Grade* 3,4 | Grade 1, 2 | Grade* 3,4 | ||||||
|
|
|||||||||
| No. | (%) | No. | (%) | No. | (%) | No. | (%) | ||
| Anemia | 47 | 90.4 | 1 | 1.9 | 50 | 92.6 | 0 | 0 | 0.31 |
| Neutropenia | 11 | 21.2 | 14 | 26.9 | 13 | 24.1 | 11 | 20.4 | 0.43 |
| Thrombocytopenia | 15 | 28.8 | 0 | 0 | 10 | 18.5 | 1 | 1.9 | 0.32 |
| Acute kidney injury | 16 | 30.8 | 0 | 0 | 19 | 35.2 | 0 | 0 | / |
| Nausea/vomiting | 19 | 36.5 | 1 | 1.9 | 20 | 37.0 | 3 | 5.6 | 0.33 |
| Peripheral ischemia | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.9 | 0.32 |
| Grade 1 | Grade 2 | Grade 1 | Grade 2 | ||||||
| Alopecia | 11 | 21.1 | 8 | 15.4 | 7 | 13.0 | 23 | 42.6 | 0.002 |
n = number of patients; No. = number;
*
statistical significance for grade 3, 4