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. 2014 Oct 1;25(19):3006–3016. doi: 10.1091/mbc.E14-05-0965

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© 2014 Tang et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 4: — Stronger cross-linking interactions promote actin cable formation in simulations (Supplemental Videos S2 and S3). (A) Steady-state configurations under different cross-linking spring constant (k_crslnk) and cross-linking interaction range (r_crslnk). (B) Bundled actin filament percentage increases with increasing r_crslnk and k_crslnk. (C) Cable number as a function of r_crslnk and k_crslnk. In B and C, error bars are SEM from five runs. (D) Polarity of actin filaments in cables varies with cross-linking parameters. In “weak” regions, most actin filaments are unbundled. In “strong” regions, most filaments are bundled in either primarily parallel or antiparallel orientations. Antiparallel orientations occur due to bundling of filaments that grow from different cell tips.