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. 2014 Nov 5;25(22):3497–3500. doi: 10.1091/mbc.E14-09-1347

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© 2014 Flamholz et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 1: — Which is larger, mRNA or the protein for which it codes? When we ask, most peoples' instinct is to say that proteins are larger. As seen in this figure, the opposite is overwhelmingly the case. The mRNA for actin is more massive and has a larger geometric size than the actin monomers for which it codes because the mass of a codon of mRNA is an order of magnitude greater than that of the average amino acid.