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. 2014 Nov 5;25(22):3497–3500. doi: 10.1091/mbc.E14-09-1347

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© 2014 Flamholz et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 2: — Back-of-the-envelope calculation of the ATP demand for motility of a cell. Actin filaments criss-cross the leading edge of a motile keratocyte, and their dynamic polymerization results in a net forward motion with a speed of 0.2 μm/s. (Electron micrographs adapted from Svitkina et al., 1997.)