Table 2.
Mean expression fold differences of TP and PERI constructs
| Gene | TP PS/PERI PS | TP 7/PERI 7 | TP 45/PERI 45 |
|---|---|---|---|
|
Scx
|
10.55
a
|
94.49
b
|
29.58
b
|
|
Tnmd
|
2.07 |
20.90
b
|
12.90
b
|
|
Emcn
|
0.03
b
|
0.80 |
0.23 |
|
Bgn
|
1.13 |
3.66 |
1.54 |
|
Dcn
|
4.92
b
|
6.18
b
|
4.44
b
|
|
Col1a1
|
1.76 |
5.58
b
|
4.75
a
|
|
Col3a1
|
2.51
a
|
3.30
b
|
2.63 |
|
Col5a1
|
0.82 |
2.57 |
2.26
a
|
|
Col11a1
|
2.71 |
97.40
b
|
5.40
a
|
|
Col12a1
|
0.87 |
3.61
b
|
1.62 |
| Col14a1 | 2.09 | 13.42 b | 0.44 |
Expression fold differences represent the ratio of means of (Target Gene/Actb)Group A/(Target Gene/Actb)Group B. PERI: peritenon-derived progenitors; TP: tendon proper-derived progenitors. Days in culture: pre-seeded (PS), 7 days in construct (7), 45 days in construct (45). Statistical significance of fold changes are in bold (aP <0.05; bP <0.01); two-tailed unpaired Mann–Whitney-Wilcoxon tests were performed. Graphical representations of the data are found in Figure 4.