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. 2014 Jul 12;7:49. doi: 10.1186/s13045-014-0049-5

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Copyright © 2014 Wang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons AttributionLicense (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution,and reproduction in any medium, provided the original work is properly credited. The CreativeCommons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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IMP3 overexpression in tubal serous tubal intraepithelial carcinoma and invasive serous carcinoma. IMP3 signatures (single arrow, right) shows morphologically bland cells (single arrow, left), which exists in anatomic continuity with tubal serous intraepithelial carcinoma (double arrows). The IMP3 is also diffusely positive in the invasive component of the serous carcinoma (triple arrows), which is located adjacent to the tubal fimbria in a case with PSC.