TABLE 3.

Common findings in direct immunofluorescence for autoimmune blistering diseases

DERMATOSIS	DIF FINDINGS	IIF FINDINGS
Pemphigus foliaceus/vulgaris	Intercellular IgG and C3.	Intercellular IgG
Paraneoplastic pemphigus	Weak intercellular IgG and linear C3; granulous BMZ deposits.	Intercellular IgG +/- linear BMZ. Epithelial surface staining on rat bladder
IgA pemphigus	Intercellular IgA	Intercellular IgA
Hailey-Hailey disease	Negative	Negative
Bullous pemphigoid	Linear IgG and C3 at BMZ.	Linear IgG at BMZ. SS: epidermal
Epidermolysis Bullosa Acquisita	Linear IgG and C3 at BMZ +/-IgA , IgM	Linear IgG. SS: dermal
Mucous membrane pemphigoid	Linear IgG, C3 and IgA at BMZ.	Linear IgG at BMZ
IgA linear dermatosis	Linear IgA at BMZ.	Linear IgA at BMZ. SS: epidermal, dermal (both)
Dermatitis herpetiformis	Granular IgA deposits in the dermal papillae +/- C3	IgA class endomysial antibody
Lichen planus pemphigoid	Linear IgG and C3 at BMZ. Cytoid bodies.	Linear IgG at BMZ. SS: epidermal