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. 2014 Nov 13;10(11):e1004790. doi: 10.1371/journal.pgen.1004790

Table 2. Motifs loss rates within and outside modern human recombination hotspots (HapMap).

Motifs Branch Na Rateb pc # obs. lossd # exp. losse # dBGC lossf
HM CM HM CM
Within hotspots Chimpanzee 1272 724 5.5% 5.4% 0.994
Hominini 1272 724 3.9% 4.3% 0.792
Denisovan 1222 693 0.8% 0.4% 0.485
Human 1222 693 3.5% 0.6% 1.2×10−4 43 7 36
Outside hotspots Chimpanzee 3167 3669 5.2% 4.9% 0.605
Hominini 3167 3669 4.9% 4.0% 0.109
Denisovan 3013 3521 1.1% 0.5% 0.024 32 15 17
Human 3013 3521 1.2% 0.4% 3.3×10−4 35 12 23
a

Intact motif count at ancestral node of the branch (cf. Figure 1).

b

Motif loss rate along the branch.

c

P-value of proportion test comparing HM vs. CM loss rates along the branch.

d

Number of observed HM losses.

e

Number of HM losses expected in absence of dBGC (i.e. based on CM loss rate).

f

Estimated number of HM losses caused by dBGC (obs. - exp.). NB: these values are reported only for lineages showing evidence of dBGC (p<0.05).