Table 1. All parameters used in the model (including the neural and dopamine components) are provided according to their notation used in the paper, with their description, their value, and their basic units.
Parameter | Description | Value | Units |
Mean opening threshold of Ca channels | −0.01 | mV | |
Variance of of number of open Ca channels | 0.15 | mV | |
Average conductance of Ca channels | 1.1 | mS/ms | |
Nernst potential of Ca channels | 1.0 | mV | |
Mean opening threshold of K channels | 0.0 | mV | |
Variance of number of open K channels | 0.3 | mV | |
Average conductance of K channels | 2.0 | mS/ms | |
Nernst potential of K channels | −0.7 | mV | |
Mean opening threshold of open Na channels | 0.3 | mV | |
Variance of number of open Na channels | 0.15 | mV | |
Average conductance of Na channels | 6.7 | mS/ms | |
Nernst potential of Na channels | 0.53 | mV | |
Nernst potential of leak channels | −0.5 | mV | |
Average conductance of leaky ions | 0.5 | mS/ms | |
Mean potential of firing excitatory neurons | 0.54 | mV | |
Mean potential of firing inhibitory neurons | 0.0 | mV | |
Dispersion of potential of firing excitatory neurons | 2.0 | mV | |
Dispersion of potential of firing inhibitory neurons | 0.7 | mV | |
Noise current amplitude | 0.3 | ms−1 | |
Excitatory-to-excitatory strength | 0.4 | mS | |
Excitatory-to-inhibitory strength | 2.0 | mS | |
Inhibitory-to-excitatory strength | mS | ||
Excitatory noise input strength | mS | ||
Inhibitory noise input strength | 0.4 | mS | |
Temperature scaling factor of K channels | 0.7 | ||
Relaxation time of K channels | 1.0 | ms | |
NMDA-to-AMPA strength | 0.25 | ||
Maximum rate of dopamine re-uptake | 0.004 | mM/ms | |
Michaelis–Menten constant | 0.125 | mM | |
Tonic dopamine level | 0.05 | mM | |
Minimum dopamine production rate | 0.0005 | mM/neural firing | |
Maximum dopamine production rate | 0.01 | mM/neural firing | |
Dopamine antagonist strength | 0.2 | mM−1 | |
Maximum dopamine gain | 50 | ||
Minimum dopamine gain | 1.0 | ||
Maximum firing rate of exitatory neurons | 1 | kHz | |
Maximum firing rate of inhibitory neurons | 1 | kHz | |
Inhibitory noise current scaling factor | 0.1 |
Abbreviations: mV = Millivolt, mS = Millisiemens, ms = Millisecond, mM = Millimole, kHz = Kilohertz.