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. 2014 Jun 25;14:169. doi: 10.1186/1471-2180-14-169

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Copyright © 2014 Rydzewski et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Genetic organization of T6 secretion systems in Francisella. Organization of the FPI island of Ft. novicida U112 (A) and of genomic islands I (B) and II (C) encoding putative T6-like secretion systems of Francisella isolate W12-1067. Genomic island I is integrated between genes pyrD and tyrA in W12-1067 and Ft. novicida U112, whereas it is integrated between F7308_1884 und F7308_1920 in Francisella strain TX077308 (F-TX077308). Genomic island II is integrated between rpsU and glmS in W12-1067 and is not present in Ft. novicida U112 and Francisella strain TX077308. Genes (ORFs) are indicated by arrows. Gene names are given below the genes, and the protein-encoding gene (peg) numbers are given in Table 5. Genes encoding homologous proteins are boxed in the same color, with the exception of pink (mobile elements) and black (conserved core genome genes).