Table 1.
Multiple regression analysis of the effect of endogamy, mtDNA, age, and milk yield, on levels of lymphocytes in peripheral blood of cows*
| Lymphocytes | R 2 (%) | Parameter | Coefficient | 95% confidence interval | P value |
|---|---|---|---|---|---|
|
CD4
+
cells |
33.32 |
Endogamy |
-0.3363 |
-1.001 to 0.3284 |
0.3120 |
| mtDNA |
-0.6537 |
-5.304 to 3.996 |
0.7774 |
||
|
Age |
0.003929 |
0.001868 to 0.005989 |
0.0004 |
||
| Milk yield |
0.008814 |
-0.003647 to 0.02128 |
0.1602 |
||
|
CD21
+
cells |
28.94 |
Endogamy |
0.5605 |
0.04471 to 1.076 |
0.0339 |
| mtDNA |
2.119 |
-1.489 to 5.728 |
0.2417 |
||
|
Age |
-0.00181 |
-0.003409 to -0.0002116 |
0.0275 |
||
| Milk yield |
-0.00960 |
-0.01927 to 0.00007 |
0.0515 |
||
|
γδ
high
T cells |
27.56 |
Endogamy |
-0.1186 |
-0.3202 to 0.08306 |
0.2410 |
| mtDNA |
0.6985 |
-0.7122 to 2.109 |
0.3223 |
||
|
Age |
-0.000941 |
-0.001566 to -0.0003161 |
0.0042 |
||
| Milk yield |
0.001463 |
-0.002318 to 0.005243 |
0.4382 |
||
|
γδ
low
T cells |
22.65 |
Endogamy |
0.01741 |
-0.1262 to 0.1610 |
0.8074 |
| mtDNA |
0.7841 |
-0.2208 to 1.789 |
0.1224 |
||
|
Age |
0.0006863 |
0.0002410 to 0.001132 |
0.0034 |
||
| Milk yield |
0.001075 |
-0.001618 to 0.003769 |
0.4238 |
||
|
CD4
+
/CD8
+
ratio |
26.34 |
Endogamy |
-0.01696 |
-0.07484 to 0.04093 |
0.5566 |
| mtDNA |
-0.05224 |
-0.4572 to 0.3528 |
0.7953 |
||
|
Age |
0.0003006 |
0.0001211 to 0.0004800 |
0.0016 |
||
| Milk yield |
0.0001360 |
-0.0009493 to 0.001221 |
0.8010 |
||
| T/B cell ratio | 36.41 | Endogamy |
-0.2270 |
-0.4592 to 0.005096 |
0.0549 |
| mtDNA |
-1.311 |
-2.935 to 0.3127 |
0.1103 |
||
|
Age |
0.001021 |
0.0003019 to 0.001741 |
0.0066 |
||
| Milk yield | 0.005461 | 0.001109 to 0.009813 | 0.0153 |
*Significant differences at P < 0.05 are highlighted in italic format. CD8+, and γδ T lymphocytes did show any significant correlation.