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. 2014 Apr 1;14:117. doi: 10.1186/1472-6882-14-117

Table 1.

Effect of dichloromethane crude extract of aerial parts of A. abyssinica on parasitaemia and mean survival time of T. congolense infected mice

Treatment Dose (mg/kg) Parasitaemia level (log number)/ml
Mean survival time (days)
D0 D2 D4 D6 D8 D10 D12 D14
DCM ext
100
6.68 ± 0.23
7.08 ± 0.25
7.57 ± 0.26bc
7.83 ± 0.14bcd
6.31 ± 0.46cd
6.70 ± 1.37c
7.31 ± 0.44cd
6.41 ± 1.34c
34.33 ± 4.63
DCM ext
200
7.05 ± 0.18
7.04 ± 0.23
5.65 ± 1.18bc
3.80 ± 1.20a
3.92 ± 1.37a
6.70 ± 0.30c
6.78 ± 0.39c
7.07 ± 0.32c
37.83 ± 3.49
DCM ext
400
7.00 ± 0.30
6.95 ± 0.26
4.90 ± 0.98ac
2.80 ± 1.26a
1.95 ± 1.24a
3.70 ± 1.17a
4.85 ± 0.99abc
4.95 ± 1.01a
40.67 ± 2.42
DA
3.5
7.09 ± 0.06
1.25 ± 1.25
1.90 ± 1.20a
3.30 ± 1.48a
4.60 ± 1.48c
6.12 ± 1.26c
7.41 ± 0.40cd
7.92 ± 0.27c
36.83 ± 4.36
DA
28
7.13 ± 0.05
0.00 ± 0.00
0.00 ± 0.00a
0.00 ± 0.00a
0.00 ± 0.00ab
0.00 ± 0.00f
0.90 ± 0.90e
1.85 ± 1.17f
42.00 ± 0.00
Distilled water 1 ml 6.94 ± 0.26 7.97 ± 0.12 8.67 ± 0.10 8.54 ± 0.07 8.46 ± 0.17 8.70 ± 0.06 8.14 ± 0.27 8.45 ± 0.21 34.33 ± 6.15

Values are mean ± SEM; n = 6; D = day; D0 = the day treatment commenced; SEM = standard error of mean; DCM = Dichloromethane; ext = extract; DA = Diminazene aceturate; All superscripts indicate significance at p < 0.05 (a = compared to negative control; b = compared to 3.5 mg/kg DA; c = compared to 28 mg/kg DA; d = compared to 400 mg/kg; e = compared to all groups, f = compared to all groups but 400 mg/kg).