Table 3.
Fitted Bayesian log-normal survival model for Event-Free Survival in 215 patients, including 67 patients treated with BuCy2 and 148 with treated Bu-Flu.
| Variable | Mean | SD | Posterior 95% Credible Interval | Probability of a Beneficial Effect | |
|---|---|---|---|---|---|
|
| |||||
| 2.50% | 97.50% | ||||
| Intercept | 1.622 | 0.583 | 0.491 | 2.752 | - |
| Cyto = bad (vs. Other) | −0.090 | 0.287 | −0.660 | 0.473 | 0.386 |
| Disease status = CR (vs. not in CR) | 0.501 | 0.341 | −0.158 | 1.162 | 0.932 |
| Allo type = Sib/Other Rel (vs. Unrelated) | 0.230 | 0.279 | −0.320 | 0.781 | 0.799 |
| Age | −0.011 | 0.011 | −0.033 | 0.012 | 0.171 |
| PB Blast = 0 (vs. > 0) | 1.307 | 0.336 | 0.650 | 1.965 | 1.000 |
| PB PLT | 0.002 | 0.001 | 0.000 | 0.004 | 0.961 |
| Confounded Bu-Flu (vs.BuCy2) Effect | 0.416 | 0.295 | −0.141 | 1.011 | 0.922 |
| R | 0.327 | 0.045 | 0.248 | 0.424 | - |
Abbreviations: Cyto, cytogenetics; PB, peripheral blood, Allo, allogeneic; Sib, sibling; Rel, related; PLT, platelet; CR, complete remission)