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. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Magn Reson Imaging. 2009 Apr 2;27(6):760–778. doi: 10.1016/j.mri.2009.01.003

Table 3.

MRS-MRI: Pearson correlation coefficients between the size of brain regions and absolute Cho and NAA concentrations in the left hippocampus and right white matter voxels

Brain structure Choline concentration (mM)
 NAA Concentration (mM)
Left hippocampus
voxel hCho		 Right white matter
voxel wCho		 Left hippocampus
voxel hNAA		 Right white matter
voxel bNAA
Total brain volume (cm3) .270** .134 .042 .187
Total brain midsagittal area (cm2) .188 .200 .166 .142
Frontal lobe volume (cm3) .320** .208 .028 .159
Frontal lobe gray matter volume (cm3) .287** .151 .095 .126
Frontal lobe white matter volume (cm3) .298** .263* − 0.42 .203
Corpus callosum
  Midsagittal area (cm2) .280** .448** .141 .162
  Length (cm) .258* .363** .036 .104
  Region 1: genu midsagittal area (cm2) .145 .310** .052 .125
  Region 2: midsagittal area (cm2) .071 .263** .074 .147
  Region 3: midsagittal area (cm2) .245* .379** .028 .208*
  Region 4: midsagittal area (cm2) .257* .257* .063 .071
  Region 5: splenium midsagittal area (cm2) .189 373** .006 .071
Cerebellar vermis
  Midsagittal area (cm2) .197 .197 −.043 .097
  Lobules 1–5: midsagittal area (cm2) .114 .277** −.121 .112
  Lobules 6–7: midsagittal area (cm2) .307** .075 .075 .033
  Lobules 8–10: midsagittal area (cm2) −.028 .144 −.104 .102
Right caudate volume (cm3) .079 −.019 −.078 .130
Left caudate volume (cm3) .005 −.027 −.067 −.008
Total caudate volume (cm3) .041 −.023 −.073 .059
Right putamen volume (cm3) .285** .193 .011 .136
Left putamen volume (cm3) .169 .135 .047 −.054
Total putamen volume (cm3) .243* .175 .030 .046
Right hippocampus volume (cm3) .077 .195 .049 .137
Left hippocampus volume (cm3) .220* .155 .124 .082
Total hippocampus volume (cm3) .154 .180 .090 .112
*

P<.05.

**

P<.01.