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. 2014 Nov 13;9(11):e110954. doi: 10.1371/journal.pone.0110954

Figure 5. Times required to determine the distance matrix using NW and GAFD.

Figure 5

A 10,000 nt random sequence was created. Using this sequence as template, another was created that included 10 random substitutions. The previously created sequence then became a template for the creation of a new sequence with 10 new random substitutions in non-mutated bases. The process was repeated until 20% of the sequence had changed. Then, both NW and GAFD were used to build distance matrices with an increasing number of sequences and the computer time was registered. Results are plotted on a logarithmic scale.