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. 2014 Nov 13;8(11):e3309. doi: 10.1371/journal.pntd.0003309

Figure 1. Phylogenetic tree using representatives of the ENTPDases from mammals and Trypanosomatids (Leishmania and T. cruzi).

Figure 1

ENTPDase sequences were aligned by the CLC workbench program and used to construct the phylogenetic tree using the Neighbor Joining method with bootstrap analysis (number in the branches). Mus musculus (Mm); Homo sapiens (Hs). Trypanosomatids have two ENTPDases with exception of T. cruzi, which has only one ENTPDase in databank. Trypanosomatid ENTPDases are more similar to mammalian ENTPDases isoforms 5 and 6 and are grouped at the upper branch of the tree.