Table 2. Descriptive data from the region of interest (ROI) analysis using cropped templates.

	ROI size	Reference group			Multiple Sclerosis group
Structure	(voxels)	R (s)	R (s)	PD (%)	R (s)	R (s)	PD (%)
Lateral ventricles	96	0.290.33	3.42.9	969	0.200.17	1.71.4	995
Insula	1634	0.820.30	9.02.7	838	0.730.35	8.03.2	849
Cingulate cortex	7140	1.000.32	10.42.1	798	0.870.35	9.32.8	8210
Caudate nucleus	1000	1.030.36	10.63.1	808	0.640.45	6.94.4	8710
Cortical gray matter	306 1	.010.53	10.03.1	7717	0.890.53	8.93.5	7917
Pons	2654	1.060.43	9.83.5	7611	0.940.50	8.64.2	7814
Putamen	1252	1.290.18	12.91.2	745	1.250.21	12.41.5	746
Mid brain	2126	1.270.25	11.72.2	736	1.240.26	11.42.4	747
Thalamus	1998	1.340.15	12.71.1	725	1.220.28	11.72.4	757
Occipital white matter	4608	1.220.36	11.61.9	749	1.130.34	11.12.2	769
Frontal white matter	26450	1.300.37	11.61.9	7210	1.180.39	10.82.4	7410
Parietal white matter	6706	1.310.34	11.61.7	729	1.180.38	10.82.3	7410
Sublobar white matter	3040	1.330.40	11.02.7	7010	1.190.46	9.93.3	7412
White matter	78549	1.350.34	11.71.7	719	1.220.37	10.82.3	749
Corpus callosum	770	1.310.53	10.33.4	7012	1.180.53	9.33.6	7213

The table shows ROI sizes, mean R, R, and proton density (PD) values, and standard deviations of 15 pre-defined structures in the Montreal Neurological Institute (MNI) standard brain template. The ROIs were cropped with 2 mm from the standard brain templates. All comparisons between the reference group and the multiple sclerosis group were highly significant, p0.001.