Table 2. Incidence of diabetes in relation to quartiles of blood cadmium concentrations at baseline in middle-aged men (n = 1831) and women (n = 2754).
| MDC | Quartiles of cadmium | ||||
| Q1 | Q2 | Q3 | Q4 | P, trend | |
| Diabetes, n (per 1000 person-years) | 156 (8.8) | 144 (8.1) | 160 (9.2) | 162 (9.8) | |
| HR (CI)* | 1.00 | 0.92 (0.74–1.16) | 1.05 (0.84–1.31) | 1.14 (0.91–1.41) | 0.16 |
| HR (CI)** | 1.00 | 0.88 (0.70–1.11) | 0.99 (0.79–1.25) | 1.11 (0.82–1.49) | 0.51 |
| Men (n = 1831) | n = 457 | n = 458 | n = 458 | n = 458 | |
| Diabetes, n (per 1000 person-years) | 74 (10.7) | 70 (10.2) | 76 (11.4) | 79 (12.5) | |
| HR (CI)* | 1.00 | 0.94 (0.68–1.31) | 1.06 (0.77–1.46) | 1.18 (0.86–1.61) | 0.24 |
| HR (CI)** | 1.00 | 0.82 (0.59–1.14) | 0.94 (0.67–1.32) | 0.90 (0.59–1.38) | 0.98 |
| Women (n = 2754) | n = 688 | n = 689 | n = 689 | n = 688 | |
| Diabetes, n (per 1000 person-years) | 82 (7.5) | 74 (6.8) | 84 (7.8) | 83 (8.1) | |
| HR (CI)* | 1.00 | 0.91 (0.66–1.24) | 1.04 (0.77–1.41) | 1.10 (0.81–1.50) | 0.39 |
| HR (CI)** | 1.00 | 0.93 (0.68–1.27) | 0.96 (0.70–1.31) | 1.21 (0.81–1.82) | 0.57 |
HR. hazards ratio; Cl, confidence interval.
* crude model; **model with adjustment of age, waist circumference and smoking status.