Table 1.
Study characteristics
| Study | Setting | Study period | Number of patients | Age (years) | Female (%) | Surgical admission (%) | Hospital mortality (%) |
|---|---|---|---|---|---|---|---|
| Soares, 2006 [15] |
1 ICU, Brazil |
Jan 2003 to Dec 2005 |
952 |
Mean: 58.3 |
45.3 |
63.5 |
33.5 |
| Serrato, 2007 [16] |
1 ICU, Mexico |
Jan 2006 to May 2006 |
95 |
Mean: 59 |
49.0 |
28.0 |
20.0 |
| Ledoux, 2008 [34] |
1 ICU, Belgium |
Dec 2005 to Jul 2006 |
802 |
Median: 66 |
39.4 |
71.1 |
17.5 |
| Duke, 2008 [26] |
1 ICU, Australia |
Oct 2005 to Dec 2007 |
1,741 |
Median: 66 |
47.4 |
39.4 |
11.3 |
| Tsai, 2008 [31] |
1 ICU, Taiwan |
Jan 2002 to Dec 2006 |
104 |
Mean: 51 |
42.3 |
61.4 |
76 |
| Sakr, 2008 [35] |
1 ICU, Germany |
Aug 2004 to Dec 2005 |
1,851 |
Mean: 61.6 |
36.6 |
85.8 |
9.0 |
| Metnitz, 2009 [36] |
22 ICU, Austria |
Oct 2006 to Feb 2007 |
2,060 |
Mean: 64.9 |
42.0 |
57.5 |
21.7 |
| Capuzzo, 2009 [39] |
2 ICU, Italy |
Jan 2006 to Sep 2007 |
684 |
Median: 73 |
37.0 |
81.8 |
19.6 |
| Strand, 2009 [37] |
2 ICU, Norway |
Jun 2006 to Dec 2007 |
1,862 |
Median: 63 |
36.0 |
29.4 |
23.6 |
| Alves, 2009 [17] |
1 ICU, Brazil |
Jan 2006 to Dec 2006 |
350 |
Mean: 73.4a |
48.0 |
31.1 |
30.6 |
| Mbongo, 2009 [40] |
1 ICU, Spain |
Jan 2006 to Dec 2006 |
864 |
Mean: 60.7 |
34.7 |
86.3 |
8.2 |
| Poole, 2009 [41] |
147 ICU, Italy |
Feb 2007 to Dec 2007 |
28,357 |
Mean: 65.8 |
40.7 |
53.5 |
29.6 |
| Median: 70 | |||||||
| Maccariello, 2010 [18] |
11 ICU, Brazil |
Jan 2007 to Jul 2008 |
244 |
Mean: 69.5 |
43.0 |
19.0 |
68.0 |
| Silva Junior, 2010 [19] |
2 ICU, Brazil |
Mar 2008 to Mar 2009 |
1,310 |
Mean: 67.1 |
60.5 |
100 |
10.8 |
| Khwannimit, 2010 [27] |
1 ICU, Thailand |
Jan 2005 to Dec 2010 |
1,873 |
Median: 62 |
41.1 |
0 |
28.6 |
| Soares, 2010 [20] |
28 ICU, Brazil |
Aug 2007 to Sep 2009 |
717 |
Mean: 61.2 |
51.0 |
64.0 |
30.0 |
| Khwannimit, 2011 [28] |
1 ICU, Thailand |
Mar 2007 to Aug 2009 |
2,022 |
Median: 62 |
40.0 |
0 |
26.1 |
| Lim, 2011 [32] |
1 ICU, South Korea |
Mar 2008 to Feb 2009 |
633 |
Mean: 60 |
37.0 |
0 |
31.0 |
| Costa e Silva, 2011 [21] |
6 ICU, Brazil |
Nov 2003 to Jun 2005 |
366 |
Mean: 57.1 |
41.0 |
23.5 |
67.8 |
| Christensen, 2011 [38] |
1 ICU, Denmark |
Jan 2007 to Dec 2007 |
469 |
NR |
66.3 |
63.5 |
17.7 |
| Juneja, 2012 [29] |
1 ICU, India |
Jul 2008 to Sep 2009 |
653 |
Mean: 58.5 |
42.1 |
0 |
15.8 |
| Nassar Junior, 2012 [22] |
3 ICU, Brazil |
Jul 2008 to Dec 2009 |
5,780 |
Median: 66 |
52.7 |
20.9 |
9.1 |
| Keegan, 2012 [25] |
3 ICU, USA |
Jan 2006 to Dec 2006 |
2,596 |
Mean: 63.2 |
45.2 |
19.8 |
10.9 |
| Nassar Junior, 2013 [23] |
3 ICU, Brazil |
Jul 2008 to Dec 2009 |
1,015 |
Median: 61 |
40.4 |
0 |
2.1 |
| De Oliveira, 2013 [24] |
1 ICU, Brazil |
May 2006 to Jan 2007 |
501 |
Mean: 46 |
34.5 |
100 |
7.8 |
| Khwannimit, 2013 [30] |
1 ICU, Thailand |
Jan 2005 to Dec 2010 |
880 |
Median: 59 |
42.4 |
30.6 |
57.4 |
| Lim, 2013 [33] |
22 ICU, South Korea |
Jul 2010 to Jan 2011 |
2,309b |
Median: 62 |
35.3 |
39.8 |
20.1 |
| López-Caler, 2013 [42] | 6 ICU, Spain | Jan 2006 to Oct 2007 | 2,171 | Mean: 61.4 | NR | 37.2 | 16.0 |
aOnly patients aged ≥60 years were included; bdevelopment cohort in which a customized SAPS III equation was developed. NR, not reported.