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. 2014 Nov 13;9(11):e112731. doi: 10.1371/journal.pone.0112731

Table 2. Patient characteristics (per protocol analysis).

Variable Treatmentgroup (n = 11) Control(n = 11) p-value(betweengroup)*
Sex (m/f) 9/2 8/3 1.000
Age (years) 71.09±5.47 65.09±12.55 0.408
Weight (kg) 84.64±11.68 83.91±12.89 0.592
Height (cm) 174.09±6.79 172.64±6.90 0.834
ECOG at baseline (0/1/2) 6/4/1 4/5/2 0.370
EQ5D visual analogue score 72.36±14.56 76.36±13.02 0.446
History of liver surgery 45.5% 45.5% 1.000
Steatosis hepatis 36.4% 18.2% 0.635
Diabetes mellitus 18.2% 27.3% 1,000
Chemotherapy pretreatment
Applied lines 1.00±0.63 1.00±0.45 1.000
no chemotherapy 18.2% 9.1% NA
1 line 63.6% 81.8% 0.672
2 lines 18.2% 9.1% NA
Prior chemotherapy
Oxaliplatin 63.6% 63.6% 1.000
Irinotecan 36.4% 36.4% 1.000
Biologicals 54.5% 54.5% 1.000
Number of treated metastases 1.91±1.04 1.45±0.52 0.382
Maximum diameter of metastases (mm) 37.18±12.91 29.45±11.79 0.146
Clinical target volume (cm3) 42.82±29.26 31.36±37.14 0.156
Number of used brachytherapy catheters 3.18±1.78 2.27±1.74 0.079
Liver volume (cm3) 1296.1±226.6 1451.3±278.6 0.401
Interval between BT and 6 weeks FU (days) 43.91±4.76 45.09±4.68 0.757
Interval between BT and 3 months FU (days) 87.34±4.52 89.55±6.15 0.505
Liver volume with a dose exposure >10 Gy (%) 22.55±14.45 11.95±10.43 0.056
Chemotherapy during follow-up 18.2% 9.1% 1.000

Continuous data: mean ± standard deviation, frequencies: counts or percent.

*Group comparison, continuous data compared by Mann-Whitney U test, frequency data compared by Pearson’s chi square test.