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. 2014 Nov 13;9(11):e112744. doi: 10.1371/journal.pone.0112744

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© 2014 Peng et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) DMOG abrogated the decrease in BMD and the deterioration in bone microarchitecture induced by OVX, as measured by micro-CT. Morphological analysis of the vasculature within the distal femur from Microfil-perfused mice. (B) OVX decreased the vessel volume at the distal metaphysic of the femur, while DMOG treatment partly restored vessel volumes.