Table 1. Demographic and clinical characteristics of the study groups.
| Characteristic | Preterm controls | Preterm preeclampsia | Term Controls | Term preeclampsia |
| (n = 36) | (n = 71) | (n = 29) | (n = 30) | |
| Women | ||||
| Age (yr) | 27.0±4.9 | 27.3±5.43 | 31.0±5.3 | 26.6±6.5†† |
| Height (m) | 162.7±3.4 | 161.3±3.3 | 162.2±5.5 | 159.4±4.4† |
| Weight (kg) | 72.5±2.7 | 79.1±4.0*** | 75.4±2.8 | 76.3±3.5 |
| Body Mass Index | 27.5±1.3 | 30.4±1.8*** | 28.7±1.4 | 30.1±2.0†† |
| Nulliparous - no. (%) | 32(88.9) | 57(80.3) | 21(72.4) | 27(90) |
| Highest SBP at Triage (mmHg) | 124.2±13.3 | 173.0±20.8*** | 117.4±7.2 | 162.1±23.0††† |
| Highest DBP at Triage (mmHg) | 80.7±12.8 | 116.3±15.6*** | 77.9±7.7 | 105.8±15.0††† |
| Gestational age at Triage (wks) | 32.9±3.0 | 33.2±3.0 | 38.6±1.0 | 38.5±1.7 |
| Gestational age at delivery (wks) | 33.8±2.4 | 33.7±2.7 | 39.0±1.0 | 38.7±1.4 |
| Proteinuria - no. (%) | 0 | 71(100%)*** | 0 | 30(100%)††† |
| ALT at Triage (U/L) | 22.4±37.2 | 45.4±95.0 | 10.5±5.6 | 19.5±21.7† |
| Creatinine at Triage (umol/L) | 40.1±7.0 | 74.6±30.2*** | 45.2±7.2 | 61.6±15.6††† |
| Uric Acid at Triage (umol/L) | 164.6±15.0 | 373.6±87.1*** | 180.4±40.0 | 298.6±70.1††† |
| Platelet Count at Triage (×109/L) | 226.7±54.4 | 161.0±74.3*** | 203.9±56.3 | 197.3±69.0 |
| Infants | ||||
| Birth weight (g) | 2157.3±529.5 | 1893.7±638.0 * | 3471.4±461.5 | 2940.7±828.2††† |
| Delivery<37wk - no. (%) | 36(100%) | 71(100%) | 0 | 0 |
| Placenta | ||||
| Placenta weight (g) | 503.6±120.6 | 453.4±99.5* | 599.7±65.1 | 531.7±71.3††† |
| Any Adverse Outcome - no. (%) | 0 | 48 (67.6) | 0 | 6 (20) |
| Maternal Adverse Outcome | ||||
| HTN+Abnormal LFTs/Platelets - no. (%) | 0 | 13 (18.3) | 0 | 1 (3.3) |
| HTN+DIC - no. (%) | 0 | 1 (1.4) | 0 | 1 (3.3) |
| HTN+Abruption - no. (%) | 0 | 11 (15.5) | 0 | 2 (6.7) |
| HTN+Pulmonaryedema - no. (%) | 0 | 4 (5.6) | 0 | 2 (6.7) |
| HTN+Eclampsia - no. (%) | 0 | 10 (14.1) | 0 | 1 (3.3) |
| Fetal and Neonatal Adverse Outcome | ||||
| Fetal Death - no. (%) | 0 | 4 (5.6) | 0 | 2 (6.7) |
| Neonatal Death - no. (%) | 0 | 7 (9.9) | 0 | 0 |
| Small for gestational age (<10thpercentil) - no. (%) | 0 | 34 (47.9) | 0 | 5 (16.7) |
SBP = systolic blood pressure, DBP = diastolic blood pressure, ALT = alanine transaminase, DIC = Disseminated Intravascular Coagulation
Plus–minus values are means±SD.
*P<0.05 compared with gestational age matched, preterm controls;
**P<0.01 compared with gestational age matched, preterm controls;
***P<0.001 compared with gestational age matched, preterm controls.
†
P<0.05 compared with gestational age matched, term controls;
††
P<0.01 compared with gestational age matched, term controls;
†††
P<0.001 compared with gestational age matched, term controls.