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. 2014 Nov 13;9(11):e112787. doi: 10.1371/journal.pone.0112787

Figure 3. The global effect of Cyp51 haploinsufficiency.

Figure 3

The genotype effect shown on blood lipid profile (n = 8–15) and hepatic gene expression analyses in Cyp51+/− mice compared to Cyp51+/+ matched with sex (n = 4–7) and blood lipid profile differences. The direction of arrows indicate (↑) up-regulation or (↓) down-regulation of expression in heterozygous females (♀) and males (♂). The direction of arrows shows also a trend of change in genes that did not reach statistical significance. *(p<0.1); **(p<0.05). Results are joined for all diets.