Table 1. Significant differences in gross phenotype between Cyp51+/− and Cyp51+/+ mice.
Females Cyp51+/− | Females Cyp51+/+ | Males Cyp51+/− | Males Cyp51+/+ | |||||||
Mean | SEM | Mean | SEM | P value | Mean | SEM | Mean | SEM | P value | |
FAT TISSUE/BWa , b | 0.048 | 0.002 | 0.059 | 0.004 | **0.033 | 0.065 | 0.004 | 0.065 | 0.005 | 0.984 |
LIVER/BWa , b | 4.25 | 0.058 | 4.38 | 0.075 | 0.326 | 4.51 | 0.124 | 4.13 | 0.091 | **0.029 |
HDL-CHOLESTEROL [mM] | 1.43 | 0.115 | 1.28 | 0.076 | 0.369 | 1.98 | 0.103 | 1.66 | 0.091 | * 0.069 |
LDL-CHOLESTEROL [mM] | 1.09 | 0.117 | 0.91 | 0.102 | 0.127 | 1.52 | 0.168 | 1.13 | 0.135 | **0.029 |
TOTAL CHOLESTEROL [mM] | 2.92 | 0.234 | 2.58 | 0.172 | 0.194 | 3.92 | 0.255 | 3.18 | 0.212 | **0.029 |
BW – body weight;
organ weights/body weight ratios are given in organ weight[g]*100/body weigh [g].
*p<0.1, **p<0.05.