Table 3. Significant differences between Cyp51^+/− and Cyp51^+/+ mice on each diet separately.

	LFnC Females		LFnC Males		HFnC Females		HFnC Males		HFC Females		HFC Males
parameter	FC	P.value	FC	P.value	FC	P.value	FC	P.value	FC	P.value	FC	P.value
Body Weight	0.97	0.954	1.04	0.808	1.00	0.993	1.05	0.883	0.87	**0.039	1.03	0.712
Fat Tissue/BWa , b	1.00	0.954	1.00	0.911	0.84	0.466	0.95	0.893	0.63	**0.006	1.09	0.712
Heart/BWa , b	0.95	0.954	1.04	0.828	1.07	0.589	0.94	0.835	1.11	*0.085	0.95	0.617
Spleen/BWa , b	1.03	0.954	1.17	0.808	1.09	0.993	0.94	0.966	1.00	0.578	0.79	*0.080
Liver/BWa , b	0.95	0.954	1.04	0.808	1.02	0.993	1.01	0.982	0.95	0.351	1.23	**0.001
Corticosterone	0.86	0.954	0.77	0.808	0.87	0.993	0.86	0.997	2.22	*0.085	0.60	0.617
Sqle	0.66	0.134	1.19	0.702	1.38	0.263	1.48	0.132	2.50	**0.014	1.00	0.822
Cyp51	0.41	**0.003	0.60	*0.070	0.78	0.435	0.57	**0.048	1.57	0.644	0.60	*0.090
Tm7sf2	0.80	0.151	1.10	0.506	1.29	0.108	1.08	0.662	1.47	*0.060	1.13	0.633
Nsdhl	0.79	0.288	1.16	0.677	1.81	**0.006	1.18	0.410	1.83	**0.035	1.11	0.788
Dhcr7	0.89	0.507	0.75	0.496	1.71	*0.080	1.19	0.566	0.78	0.732	1.11	0.768
Dhcr24	0.90	0.573	1.50	**0.028	0.95	0.662	1.29	*0.098	1.03	0.949	0.93	0.843
Cyp8b1	1.00	0.860	1.03	0.908	1.29	0.362	1.06	0.651	2.00	**0.011	1.04	0.663
Cyp27a1	1.02	0.709	0.85	0.317	1.16	0.381	1.07	0.798	1.59	**0.009	1.09	0.767
Cyp7b1	1.00	0.566	1.46	0.251	1.67	0.181	1.09	0.935	3.00	**0.018	0.97	0.787
Cd36	1.32	0.420	1.00	0.894	0.92	0.667	1.00	0.632	0.68	*0.063	1.39	0.194
Abcg5	2.25	*0.073	2.00	*0.069	1.67	0.272	0.60	0.159	0.57	0.235	0.74	0.338

FC – fold change calculated as a ratio between average values for Cyp51^+/− mice and average values for Cyp51^+/+ mice.

^aBW – body weight;

^borgan weights/body weight ratios are given in organ weight[g]*100/body weigh [g].