Table 3. Bone turnover outcomes.
Outcome – Univariable Analysis * | N | HIV Status | Median (95% CI) | Difference | P |
CTx (ng/mL) | 57 | HIV- | 0.19 (0.15, 0.28) | 0.12 (0.02, 0.22) | 0.007 |
61 | HIV+ | 0.31 (0.22, 0.38) | |||
Osteocalcin (ng/mL) | 58 | HIV- | 6.0 (5.4, 7.2) | −1.2 (−2.5, 0.1) | 0.06 |
61 | HIV+ | 4.9 (3.4, 5.3) | |||
Outcome – Multivariable Analysis † | N | HIV Status | Adjusted Geometric Mean (95% CI) | Geometric Mean Ratio (95% CI) | P |
CTx (ng/mL) | 56 | HIV- | 0.20 (0.15, 0.26) | 1.51 (1.09, 2.10) | 0.01 |
61 | HIV+ | 0.30 (0.23, 0.40) | |||
Osteocalcin (ng/mL) | 57 | HIV- | 6.53 (5.14, 8.30) | 0.72 (0.53, 0.97) | 0.03 |
61 | HIV+ | 4.71 (3.66, 6.08) |
*Characteristics are compared between HIV serostatus groups with Wilcoxon rank-sum test for CTx and osteocalcin.
Multivariable analysis adjusted for age, gender, race, BMI, smoking, past 30 day alcohol consumption and fracture history