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. 2014 Nov 13;10(11):e1004497. doi: 10.1371/journal.ppat.1004497

Table 3. Bone turnover outcomes.

Outcome – Univariable Analysis * N HIV Status Median (95% CI) Difference P
CTx (ng/mL) 57 HIV- 0.19 (0.15, 0.28) 0.12 (0.02, 0.22) 0.007
61 HIV+ 0.31 (0.22, 0.38)
Osteocalcin (ng/mL) 58 HIV- 6.0 (5.4, 7.2) −1.2 (−2.5, 0.1) 0.06
61 HIV+ 4.9 (3.4, 5.3)
Outcome – Multivariable Analysis N HIV Status Adjusted Geometric Mean (95% CI) Geometric Mean Ratio (95% CI) P
CTx (ng/mL) 56 HIV- 0.20 (0.15, 0.26) 1.51 (1.09, 2.10) 0.01
61 HIV+ 0.30 (0.23, 0.40)
Osteocalcin (ng/mL) 57 HIV- 6.53 (5.14, 8.30) 0.72 (0.53, 0.97) 0.03
61 HIV+ 4.71 (3.66, 6.08)

*Characteristics are compared between HIV serostatus groups with Wilcoxon rank-sum test for CTx and osteocalcin.

Multivariable analysis adjusted for age, gender, race, BMI, smoking, past 30 day alcohol consumption and fracture history