Skip to main content
. 2014 Nov 13;9(11):e112984. doi: 10.1371/journal.pone.0112984

Figure 2. Analysis of axonal regrowth and/or survival of motoneurons.

Figure 2

(A) Representative image of motoneurons labeled with Fast Blue (blue, correctly regrown into the motor branch), Fluoro Ruby (red, incorrectly regrown into the sensory branch), and merge (violet, regrown into both branches, motor and sensory). (B) Mean numbers of regenerated motoneurons (+ SEM) labeled through the motor branch only (light gray bars, “Motor”), the sensory branch only (dark gray bars, “Sensory”) and the sum of neurons labeled both through motor and sensory branches (black bars, “Total”) 12 weeks after injury in mice treated with L1 Ab 557 or PBS. In non-injured mice, retrograde tracing was performed without previous injury. In this group, no incorrectly projecting neurons (white bars, “Motor & Sensory”) are detected (nd). Ten mice per group were analyzed. Asterisks indicate differences in number of motoneurons between non-injured and injured groups. Cross-hatches show differences in number of motoneurons between groups treated with L1 Ab 557 or PBS (*p<0.05, #p<0.05, one-way ANOVA with Tukey's post hoc test).