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. 2014 Nov 14;4:7060. doi: 10.1038/srep07060

Figure 6. IL-1α acts via the IL-1R and MyD88.

Figure 6

Endometrial epithelial and stromal cells were cultured in medium with vehicle or transfected with siRNA targeting (a) IL1R1 or (b) MYD88, or with a scramble siRNA sequence, followed by treatment with control medium or medium containing 10 ng/ml IL-1α for 24 h. Supernatants were collected and the concentrations of IL-6 measured by ELISA. Data are presented as mean + SEM of 4 independent experiments. Data were analyzed by GLM ANOVA, using the Bonferroni post hoc test; values differ, *** p < 0.001, ** p < 0.01, ND = not detected.